[Esophageal and gastric variceal bleeding in the prevention of early rebleeding given enteral nutrition value after endoscopic variceal ligation and treatment]

Zhonghua Gan Zang Bing Za Zhi. 2015 Jan;23(1):46-9. doi: 10.3760/cma.j.issn.1007-3418.2015.01.011.
[Article in Chinese]

Abstract

Objective: To observe liver cirrhosis with esophageal and gastric variceal bleeding (GEVB) after endoscopic variceal ligation and treatment of early oral nutrition liquid in patients administered to reduce the risk of early rebleeding.

Methods: Seventy-eight patients with cirrhosis who received therapeutic endoscopy after GEVB and who suffered from malnutrition were randomly divided into a treatment group (oral solution group, n=40) and a control group (regular diet group, n=38).Both of the two groups received food at 12 hours after therapeutic endoscopy.After 14 days, the rates of early rebleeding rate and liver function recovery were compared for the two groups. T-test, rank test, chi-square test and Fisher's exact test were used for statistical analyses.

Results: Compared with the control group, less patients in the treatment group experienced rebleeding (0/40 vs. 5/38; x2=5.624, P=0.018); the treatment group also showed significantly improved indexes of liver function (all P less than 0.05).

Conclusion: s GEVB after endoscopic treatment with early oral nutrition liquid administration can reduce in the early rebleeding risk and improve function and malnutrition status.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Endoscopy, Gastrointestinal
  • Esophageal and Gastric Varices*
  • Gastrointestinal Hemorrhage*
  • Humans
  • Ligation
  • Liver Cirrhosis
  • Recurrence
  • Treatment Outcome