[Medial longitudinal fasciculus (MLF) syndrome in a patient with giant cell arteritis]

Rinsho Shinkeigaku. 2015;55(2):107-10. doi: 10.5692/clinicalneurol.55.107.
[Article in Japanese]

Abstract

A 76-year-old female was referred to our department because of diplopia for two months and intermittent claudication for five months. She showed medial longitudinal fasciculus (MLF) syndrome. Brain MRI (T2WI) showed multiple infarctions in the right pontine tegmentum and left paramedian midbrain. A biopsy of superficial temporal artery showed the characteristic findings of glanulomatous inflammation indicative of giant cell arteritis. We thought the mechanism of this cerebral infarction as artery to artery embolization or intracranial arteritis. Treatment with oral prednisolone (1 mg/kg/day) improved her limb claudication and normalized serum C-reactive protein level.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Administration, Oral
  • Aged
  • Cerebral Infarction / diagnosis
  • Cerebral Infarction / etiology*
  • Diffusion Magnetic Resonance Imaging
  • Diplopia / etiology*
  • Female
  • Giant Cell Arteritis / complications*
  • Giant Cell Arteritis / diagnosis
  • Giant Cell Arteritis / drug therapy
  • Giant Cell Arteritis / pathology
  • Humans
  • Intermittent Claudication / etiology*
  • Mesencephalon
  • Pontine Tegmentum
  • Prednisolone / administration & dosage
  • Syndrome
  • Temporal Arteries / pathology
  • Treatment Outcome

Substances

  • Prednisolone