Abstract
In this report, we describe the emergence of reassorted H1N1 swine influenza virus, originated from a reassortment event between the H1N1 pandemic influenza virus (H1N1p/2009) and endemic swine influenza virus in Cuban swine population. In November 2010, a clinical respiratory outbreak was reported on a pig fattening farm in Cuba. Phylogenetic analysis showed that all the genes of one of the isolate obtained, with the exception of neuraminidase, belonged to the H1N1p/2009 cluster. This finding suggests that H1N1pdm has been established in swine and has become a reservoir of reassortment that may produce new viruses with both animal and public health risks.
Keywords:
Phylogenetic analysis; Reassortant; Swine influenza virus.
Copyright © 2015 Elsevier B.V. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Cuba / epidemiology
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Genome, Viral*
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Hemagglutinin Glycoproteins, Influenza Virus / genetics
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Hemagglutinin Glycoproteins, Influenza Virus / metabolism
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Influenza A Virus, H1N1 Subtype / genetics*
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Influenza A Virus, H1N1 Subtype / metabolism
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Molecular Sequence Data
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Orthomyxoviridae Infections / epidemiology*
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Orthomyxoviridae Infections / genetics
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Orthomyxoviridae Infections / virology
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Phylogeny
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Swine
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Swine Diseases / epidemiology*
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Swine Diseases / genetics
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Swine Diseases / virology
Substances
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H1N1 virus hemagglutinin
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Hemagglutinin Glycoproteins, Influenza Virus
Associated data
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GENBANK/HE589463
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GENBANK/HE589464
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GENBANK/HE589465
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GENBANK/HE589466
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GENBANK/HE589467
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GENBANK/HE589468
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GENBANK/HE589469
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GENBANK/HE589470