Comorbidity of bipolar disorder and eating disorders

Rev Psiquiatr Salud Ment. 2015 Oct-Dec;8(4):232-41. doi: 10.1016/j.rpsm.2014.12.001. Epub 2015 Mar 3.
[Article in English, Spanish]

Abstract

Introduction: The comorbidity of bipolar disorder and eating disorders has not been studied in depth. In addition, clinical implications involved in the appearance of both disorders are very important.

Material and methods: A systematic literature review of MEDLINE published up to September 2013 was performed, analyzing all the articles that studied the comorbidity of both conditions (bipolar disorder and eating disorders) and others research that studied the efficacy of pharmacological treatment and psychotherapy to improve these illnesses.

Results: In this review we found a high comorbidity of bipolar disorder and eating disorders, especially of bulimia nervosa and binge eating disorder. Studies show that lithium and topiramate are 2 of the more effective pharmacological agents in the treatment of both disorders.

Conclusion: There are a lot of studies that show evidence of comorbidity of bipolar disorder and eating disorders. However, further research is needed on assessment and treatment when these conditions co-exist, as well as study into the biopsychological aspects to determine the comorbid aetiology.

Keywords: Bipolar disorder; Comorbidity; Comorbilidad; Eating disorder; Trastorno bipolar; Trastornos de la conducta alimentaria.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Bipolar Disorder / drug therapy
  • Bipolar Disorder / epidemiology*
  • Central Nervous System Agents / therapeutic use
  • Comorbidity
  • Feeding and Eating Disorders / drug therapy
  • Feeding and Eating Disorders / epidemiology*
  • Fructose / analogs & derivatives
  • Fructose / therapeutic use
  • Humans
  • Lithium / therapeutic use
  • Topiramate

Substances

  • Central Nervous System Agents
  • Topiramate
  • Fructose
  • Lithium