Assessing multilevel determinants of adoption and implementation of genomic medicine: an organizational mixed-methods approach

Genet Med. 2015 Nov;17(11):919-26. doi: 10.1038/gim.2015.7. Epub 2015 Mar 5.

Abstract

Purpose: Adoption and implementation of evidence-based genetic and genomic medicine have been slow. We describe a methodology for identifying the influence of organizational factors on adoption and implementation of these services in health-care organizations.

Methods: We illustrate a three-component, mixed-methods health services research approach, including expert panels, qualitative interviews with key informants, and quantitative surveys completed by key informants.

Results: This research approach yielded a baseline assessment of existing genetic health-care models in the Veterans Health Administration and identified organizational barriers to and facilitators of adoption. In aggregate, the panel and key informant strategies created a communication network of relevant organizational stakeholders and a detailed foundation of organizational knowledge from which to design tools and models for implementation-level genetic/genomic translation.

Conclusion: Expert panel and key informant strategies can be used to create a backdrop of stakeholder involvement and baseline organizational knowledge within which to plan translation research and to inform strategic planning and policies for adoption and implementation of genetic services in health-care organizations.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Delivery of Health Care* / methods
  • Delivery of Health Care* / organization & administration
  • Evidence-Based Medicine
  • Genetics, Medical* / methods
  • Genetics, Medical* / organization & administration
  • Genomics* / methods
  • Genomics* / organization & administration
  • Humans
  • Models, Theoretical
  • Pilot Projects
  • Translational Research, Biomedical
  • United States
  • United States Department of Veterans Affairs