Ruthenium(II)-catalyzed C-H activation/alkyne annulation by weak coordination with O2 as the sole oxidant

Angew Chem Int Ed Engl. 2015 Apr 27;54(18):5513-7. doi: 10.1002/anie.201500600. Epub 2015 Mar 3.

Abstract

Aerobic oxidative CH functionalizations of weakly coordinating benzoic acids have been accomplished with versatile ruthenium(II) biscarboxylates under ambient oxygen or air. Mechanistic studies identified the key factors controlling the elementary step of the oxidation of the ruthenium(0) complex.

Keywords: CH activation; benzoic acids; dioxygen; oxidation; ruthenium.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aerobiosis
  • Alkenes / chemistry
  • Alkynes / chemistry*
  • Benzoic Acid / chemistry*
  • Catalysis
  • Hydrogen Bonding
  • Isocoumarins / chemical synthesis*
  • Isocoumarins / chemistry
  • Molecular Structure
  • Oxidation-Reduction
  • Oxygen / chemistry*
  • Ruthenium / chemistry*

Substances

  • Alkenes
  • Alkynes
  • Isocoumarins
  • Ruthenium
  • Benzoic Acid
  • Oxygen