Abstract
Chiral ruthenium(II) complexes modified by Josiphos ligands catalyze the reaction of alkynes with primary alcohols to form homoallylic alcohols with excellent control of regio-, diastereo-, and enantioselectivity. These processes represent the first examples of enantioselective carbonyl allylation using alkynes as allylmetal equivalents.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Alcohols / chemistry*
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Alkadienes / chemistry*
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Alkynes / chemistry*
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Allyl Compounds / chemistry
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Catalysis
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Hydrogenation
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Oxidation-Reduction
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Ruthenium / chemistry*
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Stereoisomerism
Substances
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Alcohols
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Alkadienes
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Alkynes
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Allyl Compounds
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propadiene
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Ruthenium