Necrotizing soft tissue infection following a peripheral bypass

Ann Vasc Surg. 2015;29(4):843.e17-22. doi: 10.1016/j.avsg.2014.12.036. Epub 2015 Feb 27.

Abstract

Background: Necrotizing soft tissue infection (NSTI), formerly referred to as necrotizing fasciitis, is a rare but serious postoperative complication. NSTI following arterial bypass is seen only once in the literature (for a coronary artery bypass) and is not mentioned following peripheral bypass. Although surgical site infections have been studied extensively, there are limited published data on postoperative NSTI and no data for NSTI following peripheral arterial bypass.

Case presentation: Here we present the first, to our knowledge, reported instance of an NSTI following a lower extremity peripheral bypass. Despite the continued function of the bypass, the patient became rapidly systemically ill with a focus at the surgical site. Because of prompt surgical debridement, the patient survived this severe infection, though did require an above the knee amputation to control the rapid spread of the disease. The patient, a native of American Samoa, was infected with organisms infrequently associated with NSTI, Morganella morganii and Aeromonas hydrophila. This article discusses the diagnosis and treatment of this rare postoperative complication, along with a brief review of the microbiology of the disease.

Conclusions: NSTI is a rare but lethal postoperative complication. To our knowledge, this is the first reported case of an NSTI following an arterial peripheral bypass. This patient survived because of prompt and aggressive intervention.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aeromonas hydrophila / isolation & purification*
  • Aged, 80 and over
  • Amputation, Surgical
  • Anti-Bacterial Agents / therapeutic use
  • Bioprosthesis / adverse effects*
  • Blood Vessel Prosthesis / adverse effects*
  • Blood Vessel Prosthesis Implantation / adverse effects*
  • Blood Vessel Prosthesis Implantation / instrumentation
  • Cryopreservation
  • Debridement
  • Enterobacteriaceae Infections / diagnosis
  • Enterobacteriaceae Infections / microbiology*
  • Enterobacteriaceae Infections / surgery
  • Fasciitis, Necrotizing / diagnosis
  • Fasciitis, Necrotizing / microbiology*
  • Fasciitis, Necrotizing / surgery
  • Gram-Negative Bacterial Infections / diagnosis
  • Gram-Negative Bacterial Infections / microbiology*
  • Gram-Negative Bacterial Infections / surgery
  • Humans
  • Male
  • Morganella morganii / isolation & purification*
  • Peripheral Arterial Disease / diagnosis
  • Peripheral Arterial Disease / surgery*
  • Prosthesis Design
  • Prosthesis-Related Infections / diagnosis
  • Prosthesis-Related Infections / microbiology*
  • Prosthesis-Related Infections / surgery
  • Reoperation
  • Risk Factors
  • Soft Tissue Infections / diagnosis
  • Soft Tissue Infections / microbiology*
  • Soft Tissue Infections / surgery
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Ultrasonography, Doppler, Duplex

Substances

  • Anti-Bacterial Agents