A case of frosted branch angiitis in an immunocompromised child

J AAPOS. 2015 Feb;19(1):75-6. doi: 10.1016/j.jaapos.2014.08.014.

Abstract

Frosted branch angiitis is a rare vascular reaction believed to be a nonspecific immune response to an infective, neoplastic, or idiopathic insult. The clinical presentation is characteristic and typically affects children and younger adults, and the prognosis is good. We report a case of frosted branch angiitis during immune recovery in a 2-year-old boy with Langerhans cell histiocytosis on systemic immunosuppressive therapy.

Publication types

  • Case Reports

MeSH terms

  • Adenine Nucleotides / therapeutic use
  • Antimetabolites, Antineoplastic / therapeutic use
  • Arabinonucleosides / therapeutic use
  • Child, Preschool
  • Clofarabine
  • Filgrastim
  • Glucocorticoids / therapeutic use
  • Granulocyte Colony-Stimulating Factor / therapeutic use
  • Histiocytosis, Langerhans-Cell / complications
  • Histiocytosis, Langerhans-Cell / drug therapy
  • Humans
  • Immune Reconstitution Inflammatory Syndrome / complications
  • Immune Reconstitution Inflammatory Syndrome / drug therapy
  • Immunocompromised Host*
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Methylprednisolone / therapeutic use
  • Recombinant Proteins / therapeutic use
  • Retinal Vasculitis / diagnosis*
  • Retinal Vasculitis / drug therapy

Substances

  • Adenine Nucleotides
  • Antimetabolites, Antineoplastic
  • Arabinonucleosides
  • Glucocorticoids
  • Immunosuppressive Agents
  • Recombinant Proteins
  • Granulocyte Colony-Stimulating Factor
  • Clofarabine
  • Filgrastim
  • Methylprednisolone