t(14;16)-positive multiple myeloma shows negativity for CD56 expression and unfavorable outcome even in the era of novel drugs

T Narita; A Inagaki; T Kobayashi; Y Kuroda; T Fukushima; M Nezu; S Fuchida; H Sakai; N Sekiguchi; I Sugiura; Y Maeda; H Takamatsu; N Tsukamoto; D Maruyama; Y Kubota; M Kojima; K Sunami; T Ono; M Ri; K Tobinai; S Iida

doi:10.1038/bcj.2015.6

t(14;16)-positive multiple myeloma shows negativity for CD56 expression and unfavorable outcome even in the era of novel drugs

Blood Cancer J. 2015 Feb 27;5(2):e285. doi: 10.1038/bcj.2015.6.

Authors

T Narita¹, A Inagaki², T Kobayashi³, Y Kuroda⁴, T Fukushima⁵, M Nezu⁶, S Fuchida⁷, H Sakai⁸, N Sekiguchi⁹, I Sugiura¹⁰, Y Maeda¹¹, H Takamatsu¹², N Tsukamoto¹³, D Maruyama¹⁴, Y Kubota¹⁵, M Kojima¹⁶, K Sunami¹⁷, T Ono¹⁸, M Ri¹, K Tobinai¹⁴, S Iida¹

Affiliations

¹ Department of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
² Department of Hematology and Oncology, Nagoya City West Medical Center, Nagoya, Japan.
³ Division of Hematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
⁴ Department of Hematology and Oncology, Research Center for Radiation Casualty Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
⁵ Department of Hematology and Immunology, Kanazawa Medical University, Uchinada, Japan.
⁶ Department of Hematology, National Cancer Center Hospital East, Kashiwa, Japan.
⁷ Department of Hematology, Kyoto Kuramaguchi Medical Center, Kyoto, Japan.
⁸ Division of Hematology and Oncology, Department of Internal Medicine, St Marianna University School of Medicine, Kanagawa, Japan.
⁹ Division of Hematology, National Hospital Organization Disaster Medical Center, Tokyo, Japan.
¹⁰ Division of Hematology and Oncology, Toyohashi Municipal Hospital, Toyohashi, Japan.
¹¹ Department of Hematology and Oncology, Okayama University, Okayama, Japan.
¹² Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.
¹³ Oncology Center, Gunma University Hospital, Maebashi, Japan.
¹⁴ Department of Hematology, National Cancer Center Hospital, Tokyo, Japan.
¹⁵ Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan.
¹⁶ Division of Hematology/Oncology, Department of Internal medicine, Tokai University School of Medicine, Isahara, Japan.
¹⁷ Department of Hematology, National Hospital Organization Okayama Medical Center, Okayama, Japan.
¹⁸ Department of Internal Medicine III, Hamamatsu University School of Medicine, Hamamatsu, Japan.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Aged, 80 and over
CD56 Antigen / biosynthesis*
CD56 Antigen / genetics
Chromosomes, Human, Pair 14 / genetics*
Chromosomes, Human, Pair 16 / genetics*
Cyclin D1 / biosynthesis
Cyclin D1 / genetics
Female
Gene Expression Regulation, Neoplastic
Humans
Male
Middle Aged
Multiple Myeloma / drug therapy*
Multiple Myeloma / genetics
Multiple Myeloma / pathology
Neoplasm Proteins / biosynthesis
Survival Analysis
Translocation, Genetic / genetics
Treatment Outcome

Substances

CCND1 protein, human
CD56 Antigen
NCAM1 protein, human
Neoplasm Proteins
Cyclin D1