Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation

Lise J Estcourt; Simon Stanworth; Carolyn Doree; Marialena Trivella; Sally Hopewell; Michael F Murphy; Alan Tinmouth

doi:10.1002/14651858.CD010983

Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation

Cochrane Database Syst Rev. 2014:(3):CD010983. doi: 10.1002/14651858.CD010983.

Authors

Lise J Estcourt¹, Simon Stanworth¹, Carolyn Doree², Marialena Trivella³, Sally Hopewell³, Michael F Murphy⁴, Alan Tinmouth⁵

Affiliations

¹ Haematology/Transfusion Medicine, NHS Blood and Transplant, Oxford, UK.
² Systematic Review Initiative, NHS Blood and Transplant, Oxford, UK.
³ Centre for Statistics in Medicine, University of Oxford, Oxford, UK.
⁴ NHS Blood and Transplant, John Radcliffe Hospital, Oxford, UK.
⁵ Medicine (hematology) and Pathology Centre for Transfusion Research, The Ottawa Health Research Institute and the University of Ottawa, Ottawa, Canada.

Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows: To determine whether different platelet transfusion thresholds for administration of prophylactic platelet transfusions (platelet transfusions given to prevent bleeding) affect the efficacy and safety of prophylactic platelet transfusions in preventing bleeding in patients with haematological disorders after chemotherapy with or without stem cell transplantation.

Publication types

Research Support, Non-U.S. Gov't

Abstract

Publication types

Grants and funding