A two-photon fluorescent turn-on probe for nitroxyl (HNO) and its bioimaging application in living tissues

Chem Commun (Camb). 2015 Apr 4;51(26):5754-7. doi: 10.1039/c4cc10382c.

Abstract

The first two-photon fluorescent probe for specific detection of nitroxyl is designed and synthesized, and we have further demonstrated that the new two-photon fluorescent probe could be employed to image nitroxyl in living cells and tissues.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Survival
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry*
  • HeLa Cells
  • Humans
  • Liver / chemistry*
  • Liver / cytology
  • Molecular Imaging*
  • Molecular Structure
  • Nitrogen Oxides / analysis*
  • Photons*
  • Rats

Substances

  • Fluorescent Dyes
  • Nitrogen Oxides
  • nitroxyl