Can a vascular smooth muscle-derived foam-cell really change its spots?

Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):492-5. doi: 10.1161/ATVBAHA.115.305225.

Authors

Murray W Huff¹, J Geoffrey Pickering²

Affiliations

¹ From the Robarts Research Institute and Departments of Medicine, Biophysics and Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada. mhuff@uwo.ca.
² From the Robarts Research Institute and Departments of Medicine, Biophysics and Biochemistry, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada.

PMID: 25717175
DOI: 10.1161/ATVBAHA.115.305225

No abstract available

Keywords: atherosclerosis; atherosclerotic; cholesterol; macrophages; plaque.

Publication types

Editorial
Comment

MeSH terms

Animals
Cell Transdifferentiation*
Cholesterol / metabolism*
Foam Cells / metabolism*
Humans
MicroRNAs / metabolism*
Muscle, Smooth, Vascular / metabolism*
Myocytes, Smooth Muscle / metabolism*
Nuclear Proteins / metabolism*
Trans-Activators / metabolism*

Substances

MIRN145a microRNA, mouse
MicroRNAs
MIRN143 microRNA, mouse
Nuclear Proteins
Trans-Activators
myocardin
Cholesterol