Iron-catalyzed asymmetric hydrosilylation of ketones

Chem Commun (Camb). 2015 Mar 25;51(24):5073-6. doi: 10.1039/c5cc00612k.

Abstract

A series of iron complexes of chiral iminopyridine-oxazoline (IPO) ligands have been synthesized. The most sterically hindered iron catalyst exhibits excellent activity (up to 99% yield) and high enantioselectivity (up to 93% ee) in asymmetric hydrosilylation of aryl ketones.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alcohols / chemical synthesis
  • Alcohols / chemistry
  • Catalysis
  • Iron Compounds / chemical synthesis
  • Iron Compounds / chemistry*
  • Ketones / chemistry*
  • Ligands
  • Models, Molecular
  • Molecular Structure
  • Oxazoles / chemistry
  • Pyridines / chemistry
  • Stereoisomerism

Substances

  • Alcohols
  • Iron Compounds
  • Ketones
  • Ligands
  • Oxazoles
  • Pyridines