A step forward in elucidating the mystery of OCD

Sina Kohl; Lena Ebbert; Alexander Sartorius; Jens Kuhn

doi:10.1007/s00406-015-0584-2

A step forward in elucidating the mystery of OCD

Eur Arch Psychiatry Clin Neurosci. 2015 Dec;265(8):735-6. doi: 10.1007/s00406-015-0584-2. Epub 2015 Feb 24.

Authors

Sina Kohl¹, Lena Ebbert¹, Alexander Sartorius², Jens Kuhn³

Affiliations

¹ Department of Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany.
² Department of Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health (CIMH), University of Heidelberg, Mannheim, Germany.
³ Department of Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany. jens.kuhn@uk-koeln.de.

PMID: 25708456
DOI: 10.1007/s00406-015-0584-2

Abstract

Obsessive-compulsive disorder represents one of the most disabling psychiatric disorders. The underlying pathophysiology is not fully understood. In a recent Science article, Ahmari and colleagues enlighten fundamental aspects of obsessive-compulsive disorder by means of optogenetic stimulation, thereby also elucidating the usefulness of SSRI in the treatment for OCD.

Keywords: Deep brain stimulation; Obsessive compulsive disorder; Optogenetic stimulation.

Publication types

Letter
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Corpus Striatum / physiopathology*
Frontal Lobe / physiopathology*
Male
Obsessive-Compulsive Disorder / physiopathology*
Obsessive-Compulsive Disorder / psychology*
Thalamus / physiopathology*