Vascular function and cardiovascular risk factors in women with severe flushing

Maturitas. 2015 Apr;80(4):379-83. doi: 10.1016/j.maturitas.2015.01.007. Epub 2015 Jan 24.

Abstract

Cardiovascular disease is the leading cause of death in women of postmenopausal age worldwide. It is a relatively rare occurrence before the menopause and the increase in incidence coincides with the most common symptom associated with menopausal transition, hot flushing. Interest in cardiovascular disease post-menopause has largely focused on the effect of hormone therapy on risk of coronary events and stroke, with vasomotor symptoms considered merely a nuisance symptom, but recent work suggests that the presence of flushing may be a marker of underlying cardiovascular disease.

Keywords: Cardiovascular risk; Hot flushing; Vascular function.

Publication types

  • Review

MeSH terms

  • Blood Vessels / physiopathology
  • Cardiovascular Diseases / epidemiology*
  • Cardiovascular Diseases / etiology
  • Estrogen Replacement Therapy
  • Female
  • Hot Flashes / drug therapy
  • Hot Flashes / physiopathology*
  • Humans
  • Incidence
  • Postmenopause
  • Risk Factors
  • Severity of Illness Index
  • Stroke / epidemiology
  • Vasomotor System / physiopathology*