Recognition of saccharides in the NIR region with a novel fluorogenic boronolectin: in vitro and live cell labeling

Chem Commun (Camb). 2015 Mar 21;51(23):4895-8. doi: 10.1039/c4cc10425k.

Abstract

This work describes a novel mono-boronic acid derivative of a tricarbocyanine. The probe is a genuine near-infrared fluorescence emitter with improved properties such as a large Stokes shift, excellent water solubility and sensitive fluorogenicity upon binding to carbohydrates under physiological conditions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Boron Compounds / chemistry*
  • Carbohydrates / chemistry*
  • Cell Line
  • Fluorescence
  • Fluorescent Dyes / chemistry
  • Molecular Structure
  • Monosaccharides / chemistry*
  • Sensitivity and Specificity

Substances

  • Boron Compounds
  • Carbohydrates
  • Fluorescent Dyes
  • Monosaccharides
  • boronolectin