Usefulness of 18F-fluorodeoxyglucose Positron Emission Tomography-Computed Tomography in Monitoring Adhesive Capsulitis After Breast Cancer Treatment

J Comput Assist Tomogr. 2015 May-Jun;39(3):349-55. doi: 10.1097/RCT.0000000000000222.

Abstract

Objectives: We aimed to assess the usefulness of F-fluorodeoxyglucose (F-FDG) positron emission tomography-computed tomography (PET/CT) in the monitoring of adhesive capsulitis (AC), a joint problem commonly observed in the upper arm after breast cancer treatment.

Methods: This retrospective study included 230 patients who underwent F-FDG PET/CT before and after modified radical mastectomy of whom 22 patients were identified as having AC and categorized into 2 groups: with severely and mildly limited range of motion in the shoulder joint. The F-FDG uptake patterns and mean and maximum standardized uptake values (SUVs) were analyzed.

Results: The overall incidence of AC after MRM was 9.57%. The SUVs were significantly higher in patients with severely limited range of motion compared with the other group. There was no association between the SUV and radiotherapy. The F-FDG uptake pattern differed between the groups.

Conclusions: F-fluorodeoxyglucose PET/CT is useful in evaluating AC after breast cancer treatment.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Breast Neoplasms / complications
  • Breast Neoplasms / diagnosis
  • Breast Neoplasms / surgery*
  • Bursitis / diagnosis*
  • Bursitis / etiology*
  • Fluorodeoxyglucose F18*
  • Humans
  • Mastectomy, Radical / adverse effects*
  • Middle Aged
  • Multimodal Imaging / methods
  • Observer Variation
  • Positron-Emission Tomography / methods*
  • Radiopharmaceuticals
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed / methods*
  • Treatment Outcome

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18