Multidrug resistance in Pseudomonas aeruginosa isolated from nosocomial respiratory and urinary infections in Aleppo, Syria

J Infect Dev Ctries. 2015 Feb 19;9(2):210-3. doi: 10.3855/jidc.5643.

Abstract

Introduction: Pseudomonas aeruginosa represents a serious clinical challenge due to its frequent involvement in nosocomial infections and its tendency towards multidrug resistance.

Methodology: This study uncovered antibiotic susceptibility patterns in 177 isolates from inpatients in three key hospitals in Aleppo, the largest city in Syria.

Results: Exceptionally low susceptibility to most routinely used antibiotics was uncovered; resistance to ciprofloxacin and gentamicin was 64.9% and 70.3%, respectively. Contrarily, susceptibility to colistin was the highest (89.1%).

Conclusions: Multidrug resistance was rife, found at a rate of 53.67% among studied P. aeruginosa isolates.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Cross Infection / epidemiology
  • Cross Infection / microbiology*
  • Cross-Sectional Studies
  • Drug Resistance, Multiple, Bacterial
  • Female
  • Hospitals
  • Humans
  • Inpatients
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Prevalence
  • Pseudomonas Infections / epidemiology
  • Pseudomonas Infections / microbiology*
  • Pseudomonas aeruginosa / drug effects*
  • Pseudomonas aeruginosa / isolation & purification
  • Respiratory Tract Infections / epidemiology
  • Respiratory Tract Infections / microbiology*
  • Syria / epidemiology
  • Urinary Tract Infections / epidemiology
  • Urinary Tract Infections / microbiology*

Substances

  • Anti-Bacterial Agents