Reassortant highly pathogenic influenza A(H5N6) virus in Laos

Frank Y K Wong; Phouvong Phommachanh; Wantanee Kalpravidh; Chintana Chanthavisouk; Jeffrey Gilbert; John Bingham; Kelly R Davies; Julie Cooke; Debbie Eagles; Sithong Phiphakhavong; Songhua Shan; Vittoria Stevens; David T Williams; Phachone Bounma; Bounkhouang Khambounheuang; Christopher Morrissy; Bounlom Douangngeun; Subhash Morzaria

doi:10.3201/eid2103.141488

Reassortant highly pathogenic influenza A(H5N6) virus in Laos

Emerg Infect Dis. 2015 Mar;21(3):511-6. doi: 10.3201/eid2103.141488.

Authors

Frank Y K Wong, Phouvong Phommachanh, Wantanee Kalpravidh, Chintana Chanthavisouk, Jeffrey Gilbert, John Bingham, Kelly R Davies, Julie Cooke, Debbie Eagles, Sithong Phiphakhavong, Songhua Shan, Vittoria Stevens, David T Williams, Phachone Bounma, Bounkhouang Khambounheuang, Christopher Morrissy, Bounlom Douangngeun, Subhash Morzaria

Abstract

In March 2014, avian influenza in poultry in Laos was caused by an emergent influenza A(H5N6) virus. Genetic analysis indicated that the virus had originated from reassortment of influenza A(H5N1) clade 2.3.2.1b, variant clade 2.3.4, and influenza A(H6N6) viruses that circulate broadly in duck populations in southern and eastern China.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Animals
Chick Embryo
Hemagglutination Inhibition Tests
Hemagglutinin Glycoproteins, Influenza Virus / genetics
Influenza A virus / classification*
Influenza A virus / genetics*
Influenza in Birds / epidemiology*
Influenza in Birds / virology*
Laos / epidemiology
Molecular Sequence Data
Neuraminidase / genetics
Phylogeny
Poultry
Reassortant Viruses*
Viral Proteins / genetics

Substances

Hemagglutinin Glycoproteins, Influenza Virus
Viral Proteins
NA protein, influenza A virus
Neuraminidase