[Mucoepidermoid tracheo-bronchial tumors in adulthood. A series of 22 cases]

Rev Pneumol Clin. 2015 Feb;71(1):27-36. doi: 10.1016/j.pneumo.2014.09.007. Epub 2015 Feb 14.
[Article in French]

Abstract

Introduction: Mucoepidermoid tumours (TME) are rare tumours arising from the submucosal glands of the tracheobronchial tree. The majority of these tumours develop in a benign fashion but some of them are malignant. The latter can be easily mistaken for adenosquamous carcinomas.

Patients and method: We have reviewed 22 patients suffering from TME observed over a period of 25 years. Two arose from the trachea and 20 from the cartilaginous bronchi; 12 of these tumours had macroscopic and histological criteria of low-grade malignancy, 4 had macroscopic and 6 macroscopic and microscopic criteria of high grade malignancy.

Results: Prognosis of the latter was very poor and no survival observed after 6 years follow-up, a behavior similar to that observed in non-small cell lung carcinomas and adenosquamous carcinomas.

Conclusion: The best treatment of these orphan tumours remains surgery.

Keywords: Adenosquamous carcinoma; Bronches; Bronchi; Cancer adénosquameux; Chirurgie; Mucoepidermoid tumour; Surgery; Trachea; Trachée; Tumeurs muco-épidermoïdes.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Bronchial Neoplasms* / epidemiology
  • Bronchial Neoplasms* / pathology
  • Bronchial Neoplasms* / surgery
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mucoepidermoid Tumor* / epidemiology
  • Mucoepidermoid Tumor* / pathology
  • Mucoepidermoid Tumor* / surgery
  • Neoplasm Grading
  • Prognosis
  • Pulmonary Surgical Procedures / statistics & numerical data
  • Retrospective Studies
  • Survival Analysis
  • Tracheal Neoplasms* / epidemiology
  • Tracheal Neoplasms* / pathology
  • Tracheal Neoplasms* / surgery
  • Young Adult