A cautionary note on using binary calls for analysis of DNA methylation

Agnieszka Prochenka; Piotr Pokarowski; Piotr Gasperowicz; Joanna Kosińska; Piotr Stawiński; Renata Zbieć-Piekarska; Magdalena Spólnicka; Wojciech Branicki; Rafał Płoski

doi:10.1093/bioinformatics/btv090

A cautionary note on using binary calls for analysis of DNA methylation

Bioinformatics. 2015 May 1;31(9):1519-20. doi: 10.1093/bioinformatics/btv090. Epub 2015 Feb 13.

Authors

Agnieszka Prochenka¹, Piotr Pokarowski², Piotr Gasperowicz², Joanna Kosińska², Piotr Stawiński², Renata Zbieć-Piekarska², Magdalena Spólnicka², Wojciech Branicki², Rafał Płoski²

Affiliations

¹ Institute of Computer Science, Polish Academy of Sciences, Jana Kazimierza 5, Warsaw, Poland, Department of Medical Genetics, Medical University of Warsaw, Pawińskiego 3c, Warsaw, Poland, Faculty of Mathematics, Informatics and Mechanics, University of Warsaw, Banacha 2, Warsaw, Poland, Department of Immunology, Center for Biostructure Research, Medical University of Warsaw, Banacha 2, Warsaw, Poland, Central Forensic Laboratory of the Police, Aleje Ujazdowskie 7, Warsaw, Poland and Institute of Forensic Research, Westerplatte 9, Krakow, Poland Institute of Computer Science, Polish Academy of Sciences, Jana Kazimierza 5, Warsaw, Poland, Department of Medical Genetics, Medical University of Warsaw, Pawińskiego 3c, Warsaw, Poland, Faculty of Mathematics, Informatics and Mechanics, University of Warsaw, Banacha 2, Warsaw, Poland, Department of Immunology, Center for Biostructure Research, Medical University of Warsaw, Banacha 2, Warsaw, Poland, Central Forensic Laboratory of the Police, Aleje Ujazdowskie 7, Warsaw, Poland and Institute of Forensic Research, Westerplatte 9, Krakow, Poland.
² Institute of Computer Science, Polish Academy of Sciences, Jana Kazimierza 5, Warsaw, Poland, Department of Medical Genetics, Medical University of Warsaw, Pawińskiego 3c, Warsaw, Poland, Faculty of Mathematics, Informatics and Mechanics, University of Warsaw, Banacha 2, Warsaw, Poland, Department of Immunology, Center for Biostructure Research, Medical University of Warsaw, Banacha 2, Warsaw, Poland, Central Forensic Laboratory of the Police, Aleje Ujazdowskie 7, Warsaw, Poland and Institute of Forensic Research, Westerplatte 9, Krakow, Poland.

PMID: 25682069
DOI: 10.1093/bioinformatics/btv090

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't
Comment

MeSH terms

DNA Methylation*
Gene Expression Profiling*
Genome, Human*
High-Throughput Nucleotide Sequencing / methods*
Humans
Models, Statistical*
Oligonucleotide Array Sequence Analysis / methods*
Sulfites / chemistry*

Substances

Sulfites