Tomographic diffractive microscopy with agile illuminations for imaging targets in a noisy background

Opt Lett. 2015 Feb 15;40(4):573-6. doi: 10.1364/OL.40.000573.

Abstract

Tomographic diffractive microscopy is a marker-free optical digital imaging technique in which three-dimensional samples are reconstructed from a set of holograms recorded under different angles of incidence. We show experimentally that, by processing the holograms with singular value decomposition, it is possible to image objects in a noisy background that are invisible with classical wide-field microscopy and conventional tomographic reconstruction procedure. The targets can be further characterized with a selective quantitative inversion.