Differences in clinical features and outcomes between group A and group G Streptococcus -induced cellulitis

Dermatology. 2015;230(3):244-9. doi: 10.1159/000371813. Epub 2015 Feb 12.

Abstract

Background: Streptococci are the main causative agents of cellulitis, and group G Streptococcus (GGS) shares many important virulent factors with group A Streptococcus (GAS). The difference in the clinical features of GAS- and GGS-induced cellulitis, however, has not been thoroughly characterized.

Objective: Our aim was to recognize the differences in the clinical manifestations and outcomes of lower limb cellulitis caused by GAS and GGS.

Methods: We retrospectively analyzed a total of 29 patients diagnosed with GAS- or GGS-induced lower limb cellulitis during the period from January 2008 to September 2013.

Results: While the clinical manifestations of GAS-induced cellulitis were likely to be uniform, those of GGS-induced cellulitis were variable, depending on the predisposing factors. GGS-induced cellulitis occurred more frequently in older person who had chronic underlying illness.

Conclusion: We identified clinical predisposing factors that can predict the clinical course and outcomes of GGS-induced cellulitis.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cellulitis / diagnosis
  • Cellulitis / microbiology*
  • Female
  • Humans
  • Lower Extremity / microbiology
  • Male
  • Middle Aged
  • Retrospective Studies
  • Streptococcal Infections / diagnosis
  • Streptococcal Infections / microbiology*
  • Streptococcus / pathogenicity*
  • Streptococcus pyogenes / pathogenicity
  • Young Adult