Moving from tinkering in the garage to assembly line production: the manufacture of genetically modified T cells expressing chimeric antigen receptors (CARs) comes on line

Cancer Gene Ther. 2015 Mar;22(2):64-6. doi: 10.1038/cgt.2014.70. Epub 2015 Feb 13.

Author

Affiliation

¹ Division of Pediatrics, (Unit 907), The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

PMID: 25675874
DOI: 10.1038/cgt.2014.70

No abstract available

Publication types

Review

MeSH terms

Antigens, Neoplasm / genetics
Antigens, Neoplasm / immunology
Antigens, Neoplasm / therapeutic use
Cell Lineage / genetics
Cell Lineage / immunology
Gene Expression Regulation, Neoplastic
Genetic Engineering
Humans
Immunotherapy, Adoptive*
Neoplasms / immunology
Neoplasms / therapy*
Receptors, Antigen, T-Cell / genetics*
Receptors, Antigen, T-Cell / immunology
Receptors, Antigen, T-Cell / therapeutic use*
T-Lymphocytes / immunology*

Substances

Antigens, Neoplasm
Receptors, Antigen, T-Cell