Impact of a rapid microarray-based assay for identification of positive blood cultures for treatment optimization for patients with streptococcal and enterococcal bacteremia

J Clin Microbiol. 2015 Apr;53(4):1411-4. doi: 10.1128/JCM.00104-15. Epub 2015 Feb 11.

Abstract

Implementation of the Verigene Gram-positive blood culture test led to reductions in time to acceptable antibiotic overall (1.9 versus 13.2 h, respectively; P=0.04) and time to appropriate antibiotic for patients with vancomycin-resistant Enterococcus (4.2 versus 43.7 h; P=0.006) and viridans group Streptococcus (0.2 versus 7.1 h; P=0.02).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Bacteremia / diagnosis*
  • Bacteremia / microbiology
  • Case-Control Studies
  • Enterococcus / isolation & purification*
  • Gram-Positive Bacterial Infections / blood
  • Gram-Positive Bacterial Infections / diagnosis*
  • Gram-Positive Bacterial Infections / microbiology
  • Humans
  • Middle Aged
  • Oligonucleotide Array Sequence Analysis / methods*
  • Streptococcus / isolation & purification*