Induction of both P-glycoprotein and specific cytochrome P450 by aspirin eventually does not alter the antithrombotic effect of clopidogrel

Clin Pharmacol Ther. 2015 Apr;97(4):324. doi: 10.1002/cpt.32. Epub 2014 Dec 15.

Authors

M P Li¹, J Tang, Z L Zhang, X P Chen

Affiliation

¹ Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Hunan, P.R. China; Institute of Clinical Pharmacology, Central South University, Hunan Key Laboratory of Pharmacogenetics, Hunan, P.R. China.

PMID: 25669934
DOI: 10.1002/cpt.32

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't
Comment

MeSH terms

ATP Binding Cassette Transporter, Subfamily B, Member 1 / drug effects*
ATP Binding Cassette Transporter, Subfamily B, Member 1 / metabolism*
Aspirin / pharmacology*
Fibrinolytic Agents / pharmacology*
Humans
Male
Platelet Aggregation Inhibitors / pharmacology*
Ticlopidine / analogs & derivatives*

Substances

ATP Binding Cassette Transporter, Subfamily B, Member 1
Fibrinolytic Agents
Platelet Aggregation Inhibitors
Ticlopidine
Aspirin