Long-term plasma exchange in pediatric CIDP

Marta Lucchetta; Enrico Vidal; Stefano Sartori; Marta Campagnolo; Chiara Dalla Torre; Piero Marson; Renzo Manara; Chiara Briani

doi:10.1002/jca.21384

Long-term plasma exchange in pediatric CIDP

J Clin Apher. 2015 Dec;30(6):364-6. doi: 10.1002/jca.21384. Epub 2015 Feb 7.

Authors

Marta Lucchetta¹, Enrico Vidal², Stefano Sartori², Marta Campagnolo¹, Chiara Dalla Torre¹, Piero Marson³, Renzo Manara⁴, Chiara Briani¹

Affiliations

¹ Department of Neurosciences, University of Padova, Padova, Italy.
² Department of Woman and Child Health, University of Padova, Padova, Italy.
³ Department of Apheresis Unit, Blood Transfusion Service, University of Padova, Padova, Italy.
⁴ Department of Neuroradiology, University of Padova, Padova, Italy.

PMID: 25663075
DOI: 10.1002/jca.21384

Abstract

Therapeutic plasma exchange (TPE) is not frequently used in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) because it usually gives only a short-term benefit. We report on a 16-year-old boy with renal insufficiency undergoing hemodialysis who developed CIDP and underwent TPE with dramatic long-term response to therapy. Nerve ultrasound and MRI findings are also reported. In our patient TPE was chosen because he was already undergoing hemodialysis. Though it is not considered a first-line therapy in pediatric CIDP, TPE may be a good therapeutic choice also in long-term period.

Keywords: CIDP; pediatric; plasma exchange.

Publication types

Case Reports

MeSH terms

Adolescent
Glomerulonephritis, Membranoproliferative / complications
Glomerulonephritis, Membranoproliferative / therapy
Humans
Kidney Failure, Chronic / complications
Kidney Failure, Chronic / therapy
Male
Plasma Exchange*
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / complications
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / diagnosis
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / therapy*
Renal Dialysis
Time Factors
Treatment Outcome