Spectral-domain optical coherence tomography measurements of central foveal thickness before and after cataract surgery in children

Matteo Sacchi; Massimiliano Serafino; Rupal H Trivedi; Claudia Specchia; Micol Alkabes; Francesca Gilardoni; Paolo Nucci

doi:10.1016/j.jcrs.2014.05.047

Spectral-domain optical coherence tomography measurements of central foveal thickness before and after cataract surgery in children

J Cataract Refract Surg. 2015 Feb;41(2):382-6. doi: 10.1016/j.jcrs.2014.05.047.

Authors

Matteo Sacchi¹, Massimiliano Serafino¹, Rupal H Trivedi¹, Claudia Specchia¹, Micol Alkabes¹, Francesca Gilardoni¹, Paolo Nucci²

Affiliations

¹ From the University Eye Clinic (Sacchi, Serafino, Alkabes, Gilardoni, Nucci), San Giuseppe Hospital, University of Milan, and IRCCS MultiMedica (Specchia), Milan, and the Department of Molecular and Translational Medicine (Specchia), University of Brescia, Brescia, Italy; Miles Center for Pediatric Ophthalmology (Trivedi), Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.
² From the University Eye Clinic (Sacchi, Serafino, Alkabes, Gilardoni, Nucci), San Giuseppe Hospital, University of Milan, and IRCCS MultiMedica (Specchia), Milan, and the Department of Molecular and Translational Medicine (Specchia), University of Brescia, Brescia, Italy; Miles Center for Pediatric Ophthalmology (Trivedi), Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA. Electronic address: paolo.nucci@unimi.it.

PMID: 25661132
DOI: 10.1016/j.jcrs.2014.05.047

Abstract

Purpose: To compare macular thickness before and after cataract surgery and intraocular lens (IOL) implantation in pediatric eyes.

Design: Retrospective cohort study.

Setting: University Eye Clinic, San Giuseppe Hospital, University of Milan, Milan, Italy.

Methods: The study analyzed spectral-domain optical coherence tomography (SD-OCT) images of the macula in pediatric eyes in which cataract surgery had been performed and that were examined preoperatively and 1, 3, 6, 9, and 12 months postoperatively.

Results: The mean age of the 11 patients (11 eyes) was 5.8 years ± 2.2 (SD) (range 3 to 14 years). The mean macular thickness at 1 month and 3 months was significantly higher than at baseline (273.7 ± 26.8 μm and 266.0 ± 22.8 μm, respectively, versus 244.8 ± 19.5 μm; P < .0001). It reached the baseline value after 3 months and remained stable over the 12-month follow-up. The mean thicknesses at 6, 9, and 12 months were 249.1 ± 17.6 μm, 245.7 ± 18.5 μm, and 246.2 ± 18.1 μm, respectively (P > .05 versus baseline).

Conclusions: Spectral-domain OCT was useful in evaluating the macular changes in the eyes of a cohort of pediatric patients 3 years and older. Cystoid macular edema was not observed during the 12-month follow-up.

Financial disclosure: No author has a financial or proprietary interest in any material or method mentioned.

MeSH terms

Adolescent
Child
Child, Preschool
Cohort Studies
Female
Follow-Up Studies
Fovea Centralis / pathology*
Humans
Lens Implantation, Intraocular*
Macular Edema / diagnosis
Macular Edema / etiology
Male
Phacoemulsification*
Postoperative Period
Preoperative Period
Retrospective Studies
Tomography, Optical Coherence*