Efficacy of a novel skin antiseptic against carbapenem-resistant Enterobacteriaceae

Am J Infect Control. 2015 Apr 1;43(4):380-2. doi: 10.1016/j.ajic.2014.12.007. Epub 2015 Feb 7.

Abstract

Infections caused by carbapenem-resistant Enterobacteriaceae (CRE) are increasing on a global scale. Because of the need for CRE transmission prevention and control, we sought to evaluate the efficacy of a silver-based skin antiseptic against these organisms. Using a human skin analog, a third party laboratory conducted efficacy testing. The results suggest that this product provides antimicrobial activity against CRE on human skin. Because of the unique properties, this antiseptic may be useful for daily bathing of hospitalized patients to assist in the control of CRE.

Keywords: Carbapenemase; Colloidal silver; Daily bathing; Skin antisepsis.

MeSH terms

  • Anti-Infective Agents, Local / therapeutic use*
  • Carbapenems / therapeutic use
  • Drug Resistance, Bacterial*
  • Enterobacteriaceae Infections / drug therapy*
  • Escherichia coli / drug effects
  • Humans
  • Klebsiella pneumoniae / drug effects
  • Silver / therapeutic use*
  • Skin / microbiology*

Substances

  • Anti-Infective Agents, Local
  • Carbapenems
  • colloidal silver
  • Silver