Illuminating Parkinson's therapy with optogenetics

Nat Biotechnol. 2015 Feb;33(2):149-50. doi: 10.1038/nbt.3140.

Abstract

Controlling transplanted dopamine neurons with light helps define their mechanism of action.

MeSH terms

  • Cell Differentiation / genetics
  • Dopaminergic Neurons / transplantation*
  • Embryonic Stem Cells / metabolism
  • Embryonic Stem Cells / transplantation
  • Halorhodopsins / therapeutic use
  • Humans
  • Optogenetics / methods*
  • Parkinson Disease / genetics
  • Parkinson Disease / therapy*

Substances

  • Halorhodopsins