Inflammatory bowel disease (IBD) affects women during their reproductive years and 25% become pregnant after an initial diagnosis of IBD. Many choose voluntary infertility due to concerns on the influence of disease and medical therapy on pregnancy outcome. We suggest that a multidisciplinary approach may lessen the risks involved. Pre-pregnancy consultation, with conception during the IBD remission allows a pregnancy outcome similar to the general population. During pregnancy, the continuation of regular medications (except MTX and thalidomide) and nutritional support is crucial. IBD flares during pregnancy are best treated with steroidal or anti-TNF agents, until 30-32 weeks. Breastfeeding should be encouraged. Postpartum follow-up of patients by an integrated team ensures an optimal future perinatal outcome.