Controlling the release from silver electrodes by titanium adlayers for health monitoring

Nanomedicine. 2015 May;11(4):845-53. doi: 10.1016/j.nano.2014.12.017. Epub 2015 Jan 31.

Abstract

Beside cancer, cardiovascular disease is the leading cause of deaths worldwide. For medical diagnosis electrocardiography (ECG) is only a powerful predicting tool if the sensed cardiac cycle involves a high signal to noise ratio and reduced artefacts over a long term. The interface of the electrodes to the biological system is therefore improved with a novel textile system. The textile fiber therein is a 100nm silver-coated yarn to improve the signal quality and the reliability of the ECG signals. Long term diagnosis involves a silver release to the applied tissue surface. It is known, that a high silver release can cause a cytotoxic effect on human cells. To prevent cytotoxicity but still enabling good electrical conductivity accompanied by positive antibacterial properties of silver we developed a nanoscaled TiOx adlayer. The biological and electrical properties of these novel electrode systems are investigated and described in the manuscript.

From the clinical editor: The detection of cardiovascular disease using electrocardiography (ECG) usually involves the attachment of electrodes on the skin. In this paper, the authors here described a novel textile system using silver-coated yarn, to provide the interface of the electrodes to the biological system. To prevent sustained high silver release that may lead to cytotoxicity, a nanoscaled TiOx adlayer was developed and added to the novel textile electrode.

Keywords: Body electrodes; Care/health monitoring; Cytotoxicity; Diffusion barrier; Silver release.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Delayed-Action Preparations / pharmacology
  • Electrodes
  • Electroencephalography*
  • Humans
  • Materials Testing*
  • Mice
  • Silver / pharmacology*
  • Textiles*
  • Titanium / chemistry*

Substances

  • Anti-Bacterial Agents
  • Delayed-Action Preparations
  • Silver
  • Titanium