Fibrinolysis after reperfusion of liver graft

Kin-Shing Poon; Chia-Chen Chen; Ashok Thorat; Yi-Ying Chiang; Long-Bin Jeng; Horng-Ren Yang; Te-Hung Chen; Chun-Chieh Yeh; Kuen-Bao Chen

doi:10.1016/j.aat.2014.12.001

Fibrinolysis after reperfusion of liver graft

Acta Anaesthesiol Taiwan. 2015 Mar;53(1):41-3. doi: 10.1016/j.aat.2014.12.001. Epub 2015 Jan 31.

Authors

Kin-Shing Poon¹, Chia-Chen Chen¹, Ashok Thorat², Yi-Ying Chiang¹, Long-Bin Jeng³, Horng-Ren Yang², Te-Hung Chen², Chun-Chieh Yeh², Kuen-Bao Chen¹

Affiliations

¹ Department of Anesthesiology, China Medical University Hospital, China Medical University, Taichung, Taiwan.
² Organ Transplantation Center, China Medical University Hospital, China Medical University, Taichung, Taiwan.
³ Organ Transplantation Center, China Medical University Hospital, China Medical University, Taichung, Taiwan. Electronic address: otc@mail.cmuh.org.tw.

PMID: 25649273
DOI: 10.1016/j.aat.2014.12.001

Abstract

From September 2012 to March 2013, a total of 63 adult-to-adult living donor liver transplantations were performed at our institution. All the patients were monitored for their coagulation functions using rotation thromboelastometry (ROTEM, Tem Innovations GmbH) during the procedure at the following points: preoperative baseline, 5 minutes, 30 minutes, and 120 minutes, respectively, after reperfusion of the liver graft. A total of 84.13% of cases (n = 53) revealed fibrinolysis after reperfusion of the graft and the condition was reversed after 30 minutes without any need for additional treatment. No significant coagulopathy was observed during this period in all of the cases. The result of the ROTEM finding must correlate with the clinical situation before instituting any management to avoid the risk of thrombosis of the hepatic artery.

Keywords: fibrinolysis; liver transplantation; reperfusion.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Fibrinolysis*
Humans
Liver / blood supply*
Liver Transplantation*
Reperfusion*
Thrombelastography