Prime role of IL-17A in neutrophilia and airway smooth muscle contraction in a house dust mite-induced allergic asthma model

J Allergy Clin Immunol. 2015 Jun;135(6):1643-1643.e3. doi: 10.1016/j.jaci.2014.12.1872. Epub 2015 Jan 30.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Antibodies, Neutralizing / pharmacology*
  • Antigens, Dermatophagoides / administration & dosage*
  • Asthma / chemically induced
  • Asthma / drug therapy*
  • Asthma / genetics
  • Asthma / immunology
  • Cell Movement / drug effects
  • Chemokine CCL5 / genetics
  • Chemokine CCL5 / immunology
  • Chemokine CXCL1 / genetics
  • Chemokine CXCL1 / immunology
  • Chemokine CXCL5 / genetics
  • Chemokine CXCL5 / immunology
  • Disease Models, Animal
  • Gene Expression
  • Humans
  • Interleukin-17 / antagonists & inhibitors
  • Interleukin-17 / genetics
  • Interleukin-17 / immunology*
  • Mice
  • Muscle Contraction / drug effects*
  • Muscle Contraction / immunology
  • Muscle, Smooth / drug effects
  • Muscle, Smooth / immunology
  • Neutrophils / drug effects*
  • Neutrophils / immunology
  • Neutrophils / pathology
  • Pyroglyphidae / chemistry
  • Pyroglyphidae / immunology
  • Respiratory System / drug effects
  • Respiratory System / immunology
  • Th17 Cells / drug effects
  • Th17 Cells / immunology
  • Th17 Cells / pathology
  • Th2 Cells / drug effects
  • Th2 Cells / immunology
  • Th2 Cells / pathology

Substances

  • Antibodies, Neutralizing
  • Antigens, Dermatophagoides
  • Ccl5 protein, mouse
  • Chemokine CCL5
  • Chemokine CXCL1
  • Chemokine CXCL5
  • Cxcl1 protein, mouse
  • Cxcl5 protein, mouse
  • Interleukin-17