The role of hemodynamic catheterization in the evaluation of hypertrophic obstructive cardiomyopathy: A case series

Catheter Cardiovasc Interv. 2015 Nov;86(5):903-12. doi: 10.1002/ccd.25856. Epub 2015 Feb 18.

Abstract

Confirmation of the presence and magnitude of left ventricular outflow tract (LVOT) obstruction is a critical component of the evaluation of symptoms in patients with hypertrophic cardiomyopathy (HCM). The presence of LVOT obstruction in patients with severe symptoms refractory to pharmacologic therapy identifies a subgroup of HCM patients who may benefit from septal reduction therapy. Two-dimensional echocardiography with continuous wave Doppler is the main tool for confirming the presence and severity of LVOT obstruction in HCM. However, when uncertainty remains following non-invasive evaluation, invasive hemodynamics studies are required to confirm and quantify LVOT obstruction. In this manuscript we describe a series of 6 cases in which hemodynamic catheterization is instrumental in supplementing non-invasive imaging in the assessment of LVOT obstruction in HCM.

Keywords: cardiomyopathy; catheterization; diagnostic; hemodynamics; hypertrophic; transeptal.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Aged
  • Cardiac Catheterization*
  • Cardiomyopathy, Hypertrophic / diagnosis*
  • Cardiomyopathy, Hypertrophic / physiopathology
  • Cardiomyopathy, Hypertrophic / therapy
  • Echocardiography, Doppler
  • Female
  • Hemodynamics*
  • Humans
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Recovery of Function
  • Severity of Illness Index
  • Treatment Outcome
  • Ventricular Outflow Obstruction / diagnosis*
  • Ventricular Outflow Obstruction / physiopathology
  • Ventricular Outflow Obstruction / therapy