Abstract
This lecture will describe how the properties of heparin-binding EFG-like growth factor (HB-EGF) can be utilized to protect the intestines from necrotizing enterocolitis (NEC), to augment the effects of stem cells in the treatment of NEC, and to improve the production of tissue-engineered intestine. It will also explore the role of the enteric nervous system in the development of NEC.
Keywords:
HB-EGF; Intestine; Necrotizing enterocolitis; Tissue engineering.
Copyright © 2015 Elsevier Inc. All rights reserved.
Publication types
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Lecture
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Animals, Newborn
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Enterocolitis, Necrotizing / prevention & control
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Enterocolitis, Necrotizing / therapy*
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Heparin-binding EGF-like Growth Factor / pharmacology
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Heparin-binding EGF-like Growth Factor / therapeutic use*
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Humans
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Intestines / cytology
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Intestines / drug effects*
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Protective Agents / therapeutic use*
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Rats
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Research
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Stem Cells / drug effects*
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Tissue Engineering
Substances
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Heparin-binding EGF-like Growth Factor
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Protective Agents