Differences in the erythropoiesis-hepcidin-iron store axis between hemoglobin H disease and β-thalassemia intermedia

Haematologica. 2015 May;100(5):e169-71. doi: 10.3324/haematol.2014.115733. Epub 2015 Jan 16.

Authors

Raffaella Origa¹, Mario Cazzola², Elisabetta Mereu¹, Fabrice Danjou¹, Susanna Barella³, Nicolina Giagu³, Renzo Galanello¹, Dorine W Swinkels⁴

Affiliations

¹ Ospedale Microcitemico-Department of Public Health, Clinical and Molecular Medicine, University of Cagliari, Italy.
² Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, and Department of Molecular Medicine, University of Pavia, Italy.
³ Ospedale Microcitemico-ASL 8, Cagliari, Italy.
⁴ Department of Laboratory Medicine, Radboud University medical center, Nijmegen, The Netherlands Dorine.Swinkels@Radboudumc.nl.

No abstract available

Keywords: erythropoiesis-hepcidin-iron store axis; hemoglobin H disease; β-thalassemia intermedia.

Publication types

Letter

MeSH terms

Erythropoiesis*
Growth Differentiation Factor 15 / blood
Growth Differentiation Factor 15 / metabolism
Hemolysis
Hepcidins / blood
Hepcidins / metabolism*
Humans
Iron / metabolism*
Iron Overload / metabolism
alpha-Thalassemia / blood
alpha-Thalassemia / diagnosis
alpha-Thalassemia / metabolism*
beta-Thalassemia / blood
beta-Thalassemia / diagnosis
beta-Thalassemia / metabolism*

Substances

Growth Differentiation Factor 15
Hepcidins
Iron