Age at onset of major depression and adulthood cardiovascular risk

Silvia Franco; Nicolas Hoertel; Hugo Peyre; Jorge Mario Rodríguez-Fernández; Frédéric Limosin; Carlos Blanco

doi:10.1016/j.psychres.2014.12.022

Age at onset of major depression and adulthood cardiovascular risk

Psychiatry Res. 2015 Feb 28;225(3):736-8. doi: 10.1016/j.psychres.2014.12.022. Epub 2014 Dec 20.

Authors

Silvia Franco¹, Nicolas Hoertel², Hugo Peyre³, Jorge Mario Rodríguez-Fernández⁴, Frédéric Limosin⁵, Carlos Blanco⁴

Affiliations

¹ Department of Psychiatry, New York State Psychiatric Institute/Columbia University, New York, NY 10032, USA. Electronic address: corsosi@nyspi.columbia.edu.
² Department of Psychiatry, New York State Psychiatric Institute/Columbia University, New York, NY 10032, USA; Assistance Publique-Hôpitaux de Paris (APHP), Corentin Celton Hospital, Department of Psychiatry, Paris Descartes University, PRES Sorbonne Paris Cité, 92130 Issy-les-Moulineaux, Paris, France; INSERM UMR 894, Psychiatry and Neurosciences Center, Paris Descartes University, PRES Sorbonne Paris Cité, Paris, France.
³ Assistance Publique Hôpitaux de Paris (APHP), Robert Debré Hospital, Child and Adolescent Psychiatry Department, Paris, France; Cognitive Sciences and Psycholinguistic Laboratory, Ecole Normale Supérieure, CNRS, EHESS, Paris, France.
⁴ Department of Psychiatry, New York State Psychiatric Institute/Columbia University, New York, NY 10032, USA.
⁵ Assistance Publique-Hôpitaux de Paris (APHP), Corentin Celton Hospital, Department of Psychiatry, Paris Descartes University, PRES Sorbonne Paris Cité, 92130 Issy-les-Moulineaux, Paris, France; INSERM UMR 894, Psychiatry and Neurosciences Center, Paris Descartes University, PRES Sorbonne Paris Cité, Paris, France.

PMID: 25595335
DOI: 10.1016/j.psychres.2014.12.022

Abstract

Childhood-onset compared to adulthood-onset of major depression is associated with increased rates of serious cardiovascular events, independently of cardiovascular risk factors. This could be explained by a longer duration of exposure to depression. Cardiovascular disease risk should be systematically assessed in individuals with long duration of major depression.

Keywords: Age at onset; Cardiovascular risk; Depression.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Adult
Age of Onset*
Cardiovascular Diseases / epidemiology*
Depressive Disorder, Major / epidemiology*
Female
Humans
Male
Middle Aged
Risk
United States / epidemiology

Abstract

Publication types

MeSH terms

Grants and funding