Genome Sequence of the Heteropolysaccharide-Producing Strain Lactobacillus mucosae DPC 6426

Paul M Ryan; Caitriona M Guinane; Lis E E London; Philip R Kelleher; Gerald F Fitzgerald; Noel M Caplice; R Paul Ross; Catherine Stanton

doi:10.1128/genomeA.01350-14

Genome Sequence of the Heteropolysaccharide-Producing Strain Lactobacillus mucosae DPC 6426

Genome Announc. 2015 Jan 15;3(1):e01350-14. doi: 10.1128/genomeA.01350-14.

Authors

Paul M Ryan, Caitriona M Guinane¹, Lis E E London, Philip R Kelleher², Gerald F Fitzgerald, Noel M Caplice³, R Paul Ross⁴, Catherine Stanton⁵

Affiliations

¹ Teagasc Food Research Centre, Moorepark, Fermoy, Co. Cork, Ireland.
² School of Microbiology, University College Cork, Cork, Ireland.
³ Centre for Research in Vascular Biology, University College Cork, Cork, Ireland.
⁴ Alimentary Pharmabiotic Centre, Biosciences Institute, University College Cork, Cork, Ireland.
⁵ catherine.stanton@teagasc.ie.

Abstract

Exopolysaccharide-synthesizing Lactobacillus mucosae DPC 6426 is a heterofermentative strain, which has demonstrated cholesterol-lowering properties in an animal model of lipid-driven atherosclerosis. The genome revealed a plethora of homologues linked to carbohydrate metabolism and mucin binding.