[Panic disorder and affective pathology (comorbidity aspects)]

Zh Nevrol Psikhiatr Im S S Korsakova. 2014;114(10):9-13.
[Article in Russian]

Abstract

Objective: To analyze the correlation between signs of panic disorder and depressive symptoms in affective disorders.

Material and methods: Authors studied 40 patients (23 men and 17 women, mean age 31.8 years) with mild and moderate depression comorbid with symptoms of panic disorders.

Results: It was singled out two types of the comorbidity of anxiety-depressive symptoms. The first type is characterized by anxiety-apathetic affect with the domination of ideational disorders with elements of alexithymia; panic attacks were represented by clearly-delineated paroxysms and reduced as depressive symptoms came back; affective disorder had bipolar phases. The second type of comorbidity was characterized by the somatization and asthenic symptoms in depression structure, unstable functional impairment in panic paroxysms; signs of partial agoraphobia and unipolar type of affective disorder. The complete reduction of panic attacks during the remission of depressive disorder was not found as well.

Conclusion: The types of comorbidity have different types of the dynamics of panic and depressive disorders.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Anxiety / diagnosis
  • Asthenia / diagnosis
  • Comorbidity
  • Depression / diagnosis*
  • Depression / epidemiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Panic Disorder / diagnosis*
  • Panic Disorder / epidemiology