Assessing dimerisation degree and cooperativity in a biomimetic small-molecule model by pulsed EPR

K Ackermann; A Giannoulis; D B Cordes; A M Z Slawin; B E Bode

doi:10.1039/c4cc08656b

Assessing dimerisation degree and cooperativity in a biomimetic small-molecule model by pulsed EPR

Chem Commun (Camb). 2015 Mar 28;51(25):5257-60. doi: 10.1039/c4cc08656b.

Authors

K Ackermann¹, A Giannoulis, D B Cordes, A M Z Slawin, B E Bode

Affiliation

¹ EaStCHEM School of Chemistry, Biomedical Sciences Research Complex and Centre of Magnetic Resonance, University of St Andrews, North Haugh, St Andrews KY16 9ST, UK. beb2@st-andrews.ac.uk.

PMID: 25587579
DOI: 10.1039/c4cc08656b

Abstract

Pulsed electron paramagnetic resonance (EPR) spectroscopy is gaining increasing importance as a complementary biophysical technique in structural biology. Here, we describe the synthesis, optimisation, and EPR titration studies of a spin-labelled terpyridine Zn(II) complex serving as a small-molecule model system for tuneable dimerisation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biomimetic Materials / chemical synthesis
Biomimetic Materials / chemistry*
Crystallography, X-Ray
Electron Spin Resonance Spectroscopy
Models, Molecular
Molecular Structure
Organometallic Compounds / chemical synthesis
Organometallic Compounds / chemistry*
Pyridines / chemistry*
Zinc / chemistry*

Substances

Organometallic Compounds
Pyridines
Zinc