Abstract
Under ultralow radiofrequency (RF) power, transferrin-conjugated graphene nanoparticles can thermally ablate drug- or radiation-resistant cancer cells very effectively. The results suggest that graphene-based RF hyperthermia can be an efficient method to manage drug-/radiation-resistant cancers.
Keywords:
cancer therapy; drug resistance; graphene; radiofrequency ablation; transferrin.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / pharmacology*
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Biocompatible Materials / chemistry
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Biocompatible Materials / pharmacology*
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Catheter Ablation
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Cell Line, Tumor
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Cell Survival / drug effects*
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Cell Survival / radiation effects*
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Drug Resistance, Neoplasm
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Graphite / chemistry
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Graphite / pharmacology*
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Humans
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Microscopy, Confocal
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Radio Waves*
Substances
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Antineoplastic Agents
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Biocompatible Materials
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Graphite