SAffold viruses in pediatric patients with diarrhea in Thailand

J Med Virol. 2015 Apr;87(4):702-7. doi: 10.1002/jmv.24114. Epub 2015 Jan 12.

Abstract

Saffold virus (SAFV) is a newly discovered human virus which is classified into the genus Cardiovirus of the family Picornaviridae. A total of 608 fecal specimens collected during January 2012 to December 2013 from children with diarrhea in Chiang Mai, Thailand were investigated for SAFV by RT-nested PCR and sequence analysis. Of these, nine out of 608 (1.5%) were positive for SAFVs and four genotypes were identified, SAFV1, SAFV2, SAFV3, and SAFV4. SAFV mono-infection was found in five cases (CMH-S038-12, CMH-S071-12, CMH-S102-12, CMH-N029-12, and CMH-S048-13), while co-infection with other viruses causing diarrhea was observed in four cases (CMH-S021-12, CMH-S115-12, CMH-N048-13 and CMH-N103-13). This study provides more information about the genetic background of SAFV circulating in pediatric patients with diarrhea in Thailand.

Keywords: Saffold virus; Thailand; children; diarrhea.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Cardiovirus Infections / epidemiology*
  • Cardiovirus Infections / virology*
  • Child
  • Child, Preschool
  • Cluster Analysis
  • Coinfection / epidemiology
  • Coinfection / virology
  • Diarrhea / epidemiology*
  • Diarrhea / virology*
  • Feces / virology
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Molecular Sequence Data
  • Phylogeny
  • Polymerase Chain Reaction
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sequence Analysis, DNA
  • Sequence Homology
  • Thailand / epidemiology
  • Theilovirus / isolation & purification*

Associated data

  • GENBANK/KM252720
  • GENBANK/KM252721
  • GENBANK/KM252722
  • GENBANK/KM252723
  • GENBANK/KM252724
  • GENBANK/KM252725
  • GENBANK/KM252728
  • GENBANK/KM252729
  • GENBANK/KM252730