Evidence of recent dengue exposure among malaria parasite-positive children in three urban centers in Ghana

Justin Stoler; Rupert K Delimini; J H Kofi Bonney; Abraham R Oduro; Seth Owusu-Agyei; Julius N Fobil; Gordon A Awandare

doi:10.4269/ajtmh.14-0678

Evidence of recent dengue exposure among malaria parasite-positive children in three urban centers in Ghana

Am J Trop Med Hyg. 2015 Mar;92(3):497-500. doi: 10.4269/ajtmh.14-0678. Epub 2015 Jan 12.

Authors

Justin Stoler¹, Rupert K Delimini², J H Kofi Bonney², Abraham R Oduro², Seth Owusu-Agyei², Julius N Fobil², Gordon A Awandare¹

Affiliations

¹ Department of Geography, University of Miami, Coral Gables, Florida; Department of Public Health Sciences, Miller School of Medicine, University of Miami, Miami, Florida; Kintampo Health Research Centre, Kintampo, Ghana; West African Center for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Legon, Ghana; Virology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana; Navrongo Health Research Centre, Navrongo, Ghana; Department of Biological, Environmental and Occupational Health Sciences, University of Ghana, Legon, Ghana stoler@miami.edu gawandare@ug.edu.gh.
² Department of Geography, University of Miami, Coral Gables, Florida; Department of Public Health Sciences, Miller School of Medicine, University of Miami, Miami, Florida; Kintampo Health Research Centre, Kintampo, Ghana; West African Center for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Legon, Ghana; Virology Department, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana; Navrongo Health Research Centre, Navrongo, Ghana; Department of Biological, Environmental and Occupational Health Sciences, University of Ghana, Legon, Ghana.

Abstract

Blood samples of 218 children ages 2-14 years old with confirmed malaria in hospitals across Ghana were tested for dengue virus exposure. We detected dengue-specific immunoglobulin M (IgM) antibodies in 3.2% of the children, indicating possible coinfection, and IgG antibodies in 21.6% of them, which suggests previous exposure. Correlates of exposure are discussed.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Child
Child, Preschool
Dengue / complications*
Dengue / epidemiology
Female
Ghana
Humans
Malaria / complications*
Malaria / epidemiology
Male
Urban Population*

Abstract

Publication types

MeSH terms

Grants and funding