Abstract
We describe a nucleic acid testing (NAT) platform for infectious disease diagnostics at the point-of-care, using surface acoustic waves (SAW) to perform a multiplexed loop-mediated isothermal amplification (LAMP) test for sexually transmitted diseases. The ultrasonic actuation not only enables faster NAT reactions but also provides a route towards integrating low-cost, low-power molecular diagnostics into disposable sensors.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Chlamydia trachomatis / genetics
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DNA, Bacterial / analysis*
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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Molecular Diagnostic Techniques / instrumentation
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Molecular Diagnostic Techniques / methods*
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Neisseria gonorrhoeae / genetics
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Nucleic Acid Amplification Techniques / instrumentation
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Nucleic Acid Amplification Techniques / methods*
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Nucleic Acid Denaturation
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Point-of-Care Systems
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Sexually Transmitted Diseases / diagnosis*
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Sexually Transmitted Diseases / microbiology*
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Temperature*
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Ultrasonics*