A magnetic polyaniline nanohybrid for MR imaging and redox sensing of cancer cells

Nanoscale. 2015 Feb 7;7(5):1661-6. doi: 10.1039/c4nr06340f.

Abstract

A synthetic process for constructing an organo-metal nanohybrid is described. This process uses polyaniline as a ligand in order to fabricate magnetic nanoparticles. This nanohybrid shows imaging potential uses as a magnetic resonance imaging contrast agent and a redox-sensing probe simultaneously both in vitro and in vivo.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aniline Compounds / chemistry*
  • Animals
  • Cell Line, Tumor
  • Cell Survival / drug effects
  • Contrast Media / chemistry*
  • Contrast Media / pharmacology
  • Contrast Media / toxicity
  • Humans
  • MCF-7 Cells
  • Magnetic Resonance Imaging
  • Magnetics*
  • Matrix Metalloproteinase 1 / metabolism
  • Mice
  • Nanoparticles / chemistry*
  • Neoplasms / diagnostic imaging
  • Neoplasms / pathology
  • Oxidation-Reduction
  • Radiography
  • Transplantation, Heterologous

Substances

  • Aniline Compounds
  • Contrast Media
  • polyaniline
  • Matrix Metalloproteinase 1