Abstract
The design of hydrogels with controllable drug-release properties remains challenging. Here we report a hydrogel made of hierarchical graphene oxide sheets and peptide assemblies for on-demand drug release. The hydrogel possesses high drug-sustainability and the release of drugs can be precisely and remotely controlled through external stimuli.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Antibiotics, Antineoplastic / administration & dosage
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Antibiotics, Antineoplastic / chemistry
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Antibiotics, Antineoplastic / pharmacology
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Bombyx / metabolism
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Cell Line, Tumor
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Cell Survival / drug effects
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Doxorubicin / administration & dosage
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Doxorubicin / chemistry
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Doxorubicin / pharmacology
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Drug Carriers / chemistry*
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Graphite / chemistry*
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Humans
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Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry*
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Mice
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Mice, Nude
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Neoplasms / drug therapy
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Neoplasms / pathology
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Oxides / chemistry
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Peptides / chemistry*
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Protein Structure, Secondary
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Silk / chemistry
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Spectroscopy, Fourier Transform Infrared
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Transplantation, Heterologous
Substances
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Antibiotics, Antineoplastic
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Drug Carriers
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Oxides
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Peptides
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Silk
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Hydrogel, Polyethylene Glycol Dimethacrylate
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Graphite
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Doxorubicin