GLP-1: a mediator of the beneficial metabolic effects of bariatric surgery?

Physiology (Bethesda). 2015 Jan;30(1):50-62. doi: 10.1152/physiol.00027.2014.

Abstract

There has been increasing interest in the role that gut hormones may play in contributing to the physiological changes produced by certain bariatric procedures, such as Roux-en-Y gastric bypass and sleeve gastrectomy. Here, we review the evidence implicating one such gut hormone, glucagon-like peptide-1, as a mediator of the metabolic benefits of these two procedures.

Publication types

  • Review

MeSH terms

  • Animals
  • Bariatric Surgery*
  • Gastrectomy* / methods
  • Gastric Bypass*
  • Glucagon-Like Peptide 1 / metabolism*
  • Humans
  • Obesity / metabolism*
  • Obesity / surgery*
  • Treatment Outcome

Substances

  • Glucagon-Like Peptide 1