The role of hypoxia at primary dysmenorrhea, utilizing a novel hypoxia marker--SCUBE1

J Pediatr Adolesc Gynecol. 2015 Feb;28(1):63-65. doi: 10.1016/j.jpag.2014.05.001. Epub 2014 May 20.

Abstract

Study objective: To determine the SCUBE1 levels in adolescents with primary dysmenorrhea.

Design: A prospective cross-sectional study.

Setting: A university hospital outpatient clinic, Rize, Turkey.

Participants: A total of 40 adolescent girls, 15 on menses and 25 not on menses.

Interventions and main outcome measures: Demographic features and menstrual history of the participants were assessed and blood samples were obtained for detecting the platelet volume, platelet counts, and SCUBE1 levels of the participants.

Results: No difference was detected between the 2 groups in mean platelet volume, platelet count, and SCUBE1 levels.

Conclusion: Future trials are required to investigate the relation between SCUBE1 levels and primary dysmenorrhea.

Keywords: Hypoxia; Primary dysmenorrhea; SCUBE1; adolescent.

MeSH terms

  • Adolescent
  • Biomarkers / blood
  • Calcium-Binding Proteins
  • Cross-Sectional Studies
  • Dysmenorrhea / blood*
  • Dysmenorrhea / etiology
  • Female
  • Humans
  • Hypoxia / blood*
  • Hypoxia / complications
  • Membrane Proteins / blood*
  • Platelet Count
  • Prospective Studies
  • Turkey

Substances

  • Biomarkers
  • Calcium-Binding Proteins
  • Membrane Proteins
  • SCUBE1 protein, human